CHICAGO / Apr 05, 2024 / Business Wire / MAIA Biotechnology, Inc., (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that Chairman and Chief Executive Officer Vlad Vitoc, M.D. will present at two investor conferences during the month of April: the 14th Annual LD Micro Invitational taking place April 8-9, 2024, in New York... Read More

Company recognizes significant support by board members in recent private placement CHICAGO / Mar 28, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that independent directors Cristian Luput and Ramiro Guerrero, J.D, LL.M. made individual purchases of 69,282 and 6,928... Read More

Five independent members of MAIA’s Board of Directors purchased shares in the offering CHICAGO / Mar 26, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that independent director Ms. Adelina Louie Ngar Yee made an individual purchase of 170,940 shares of the Company’s... Read More

CHICAGO / Mar 26, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that it has entered into definitive agreements for the purchase and sale of an aggregate of 578,643 shares of common stock at a purchase price of $2.295 per share, in a private placement to accredited... Read More

Dr. Smith has participated in every MAIA funding round CHICAGO / Mar 22, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA,” the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that independent director Mr. Stan V. Smith, Ph.D. made an individual purchase of 170,940 shares of the Company’s common stock as part of the Company’s... Read More

Acclaimed academic researcher has led 40+ multicenter phase 2 and phase 3 clinical studies CHICAGO / Mar 21, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced the appointment... Read More

CHICAGO / Mar 07, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced its participation in the 36th Annual ROTH Conference being held March 17-19, 2024 in Dana Point, California. Chief Executive Offer Vlad Vitoc, M.D. will host one-on-one meetings with institutional investors... Read More

THIO and ionizing radiation combination shown to significantly decrease cell proliferation and produce potent anticancer effects in highly aggressive, treatment-resistant childhood brain cancer CHICAGO / Mar 06, 2024 / Business Wire / MAIA Biotechnology, Inc., (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that Dr.... Read More

Combination THIO 180mg + cemiplimab achieved 38% overall response rate (ORR) in difficult-to-treat, third-line non-small cell lung cancer (NSCLC) ORR of 38% significantly exceeds standard of care ORR in NSCLC third-line in patients without a targetable mutation who progressed on checkpoint inhibitors and chemotherapy CHICAGO / Mar 06, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA”, the... Read More

THIO-101 Phase 2 trial nears completion with survival and response data forthcoming; exploration of multiple cancer indications and next-generation molecules continues. Shareholder Letter available in Investor Relations section of MAIA’s corporate website. CHICAGO / Mar 05, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA” or the “Company”), a clinical-stage biopharmaceutical company developing... Read More

THIO treatment leads to profound activation of innate and adaptive anti-tumor responses THIO depletes cancer initiating cells (CICs) and thus diminishes tumor initiation and metastasis-forming potential in various in vivo models THIO previously awarded orphan drug designation (ODD) by FDA for small cell lung cancer (SCLC) treatment CHICAGO / Feb 07, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA)... Read More

New patent would extend coverage and expand potential value of MAIA’s telomere-targeting platform globally CHICAGO / Jan 24, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced that the World Intellectual Property Organization (WIPO) has published MAIA’s global Patent... Read More

Lead candidate THIO maintains unprecedented disease control rates in Phase 2 non-small cell lung cancer (NSCLC) clinical trial Multiple clinical milestones ahead for THIO-101 Phase 2 trial Company enters 2024 with robust clinical pipeline in multiple hard-to-treat cancer indications CHICAGO / Jan 17, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA”, the “Company”), a clinical-stage... Read More

CHICAGO / Jan 05, 2024 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA” or the “Company”), a clinical-stage biopharmaceutical company developing telomere-targeting immunotherapies for cancer, today announced its participation in the Biotech Showcase ™ 2024 investor conference being held January 8-10, 2024, in San Francisco, California. Chairman and Chief Executive Officer Vlad Vitoc, MD, MBA will... Read More

Selected dose shows unprecedented disease control and overall response rates in a NSCLC clinical trial CHICAGO / Dec 19, 2023 / Business Wire / MAIA Biotechnology, Inc. , (NYSE American: MAIA) (“MAIA” or the “Company”), a clinical-stage biopharmaceutical company developing telomere-targeting immunotherapies for cancer, today announced dose selection for THIO-101, a Phase 2 clinical trial evaluating its lead asset, THIO, in... Read More

CHICAGO / Nov 17, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) (“MAIA” or the “Company”), a clinical-stage biopharmaceutical company developing telomere-targeting immunotherapies for cancer, today announced that it has closed its previously announced registered direct offering for the issuance and sale of an aggregate of 2,424,243 of its shares of common stock at a purchase price of $1.65 per share.... Read More

CHICAGO / Nov 15, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) (“MAIA” or the “Company”), a clinical-stage biopharmaceutical company developing telomere-targeting immunotherapies for cancer, today announced that it has entered into a definitive agreement for the issuance and sale of an aggregate of 2,424,243 of its shares of common stock at a purchase price of $1.65 per share in a registered direct... Read More

Third orphan drug designation (ODD) granted to THIO by the FDA; drug also holds ODDs for hepatocellular carcinoma and small cell lung cancer Benefits include 7 years of U.S. market exclusivity after drug approval and tax credits for qualified clinical testing Expected glioblastoma market growth from $2.2 billion to $3.2 billion globally in the next three years CHICAGO / Nov 10, 2023 / Business Wire / MAIA Biotechnology, Inc.... Read More

Substantial THIO program progress including unprecedented disease control rate (DCR) of 100% in second-line non-small cell lung cancer (NSCLC) Key THIO findings in gliomas, pediatric brain cancer, and second generation THIO-derived cancer therapies Strong pace of enrollment in THIO-101 Phase 2 trial exceeds average enrollment pace in similar NSCLC trials CHICAGO / Nov 07, 2023 / Business Wire / MAIA Biotechnology, Inc. ,... Read More

Study results warrant further in vivo in-depth investigation of THIO conjugates as second generation cancer therapies CHICAGO / Oct 30, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing telomere-targeting immunotherapies for cancer, today announced positive results from an investigational new drug-enabling study of the Company’s second-generation telomere-targeting... Read More

Unprecedented disease control rate (DCR) of 100% in second-line of treatment far surpasses standard of care (SoC) DCR of 53-64% DCR is far stronger than overall response rate (ORR) in predicting overall survival benefit, as shown in recent meta-analysis of 74 clinical trials worldwide 1 CHICAGO / Oct 24, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing... Read More

CHICAGO / Oct 19, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing telomere-targeting immunotherapies for cancer, today announced that preliminary safety and efficacy data from its ongoing Phase 2 clinical trial, THIO-101, was accepted for poster presentation at the European Society for Medical Oncology (ESMO) Congress 2023, being held in Madrid, Spain, October 20-24,... Read More

CHICAGO / Oct 17, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing telomere-targeting immunotherapies for cancer, announced its participation in the International Biochemistry Congress 2023, organized by the Turkish Biochemical Society, which will be held in Turkey from October 29 to November 1, 2023. On October 30 th , MAIA’s Chief Scientific Officer Sergei Gryaznov,... Read More

Treatment demonstrates decreased cancer cell proliferation and increased tumor sensitivity to ionizing radiation CHICAGO / Oct 12, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing telomere-targeting immunotherapies for cancer, announced that study data shows THIO’s potent anticancer activity in Diffuse Intrinsic Pontine Glioma (DIPG), one of the most aggressive tumors... Read More

49 patients dosed to date; 37 have completed at least 1 post baseline assessment THIO-101 enrollment pace currently exceeds average for similar NSCLC trials CHICAGO / Oct 10, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing telomere-targeting immunotherapies for cancer, announced today that 49 patients have been dosed in MAIA’s Phase 2 clinical trial, THIO-101,... Read More

CHICAGO / Oct 10, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing telomere-targeting immunotherapies for cancer, today announced that its lead asset THIO showed highly potent anticancer activity in gliomas, an aggressive type of brain tumor that originates from glial cells. THIO’s novel dual mechanism of action - direct telomere targeting and immune system... Read More

THIO to be Evaluated in the U.S. as Part of Current THIO-101 Global Phase 2 Clinical Trial CHICAGO / Oct 03, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing telomere-targeting immunotherapies for cancer, today announced that the U.S. Food and Drug Administration (FDA) has cleared its Investigational New Drug (IND) application for THIO to be evaluated in the U.S. as... Read More

CHICAGO / Sep 28, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical stage company developing telomere-targeting immunotherapies for cancer, today announced that its Board of Directors has approved a share repurchase program with authorization to purchase up to $800,000 of its Class A common stock through September 2024. “This share repurchase program demonstrates the confidence we have in our... Read More

Filed second provisional new composition of matter patent application for MAIA’s third entirely home-grown telomere-targeting molecule Reported 35 patients enrolled as of July 2023 in THIO-101 Phase 2 Trial First 2 patients dosed with THIO continue to be without documented disease progression for 12.2 and 11.5 months, and remarkably without any new anti-cancer treatment 10.2 and 8.5 months after concluding treatment with... Read More

Of the first 11 patients with post-baseline scans, 9 met the disease control primary endpoint at first response assessment. CHICAGO / Jul 11, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) today announced updates on disease control data in the Part A safety lead-in of its ongoing THIO-101 phase 2 trial, evaluating THIO in sequential combination with cemiplimab in patients with advanced Non-Small Cell... Read More

First 2 patients dosed with THIO continue to be without documented progression for 12.2 and 11.5 months and remarkably without any new anti-cancer treatment 10.2 and 8.5 months after concluding treatment with THIO. CHICAGO / Jul 10, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) today announced updates on preliminary survival data in the Part A safety lead-in of its ongoing THIO-101 phase 2 trial,... Read More

CHICAGO / Jun 20, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) announced today that 29 patients have been dosed in MAIA’s Phase 2 clinical trial, THIO-101, evaluating THIO in patients with advanced Non-Small Cell Lung Cancer (NSCLC). With the addition of sites in Hungary, Poland, and Bulgaria in March 2023, THIO-101 has rapidly increased the number of patients enrolled and dosed with THIO. Thirteen... Read More

Filed provisional new composition of matter patent application for MAIA’s third entirely home-grown telomere-targeting molecule CHICAGO / Jun 07, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) today announced its second broad provisional patent application covering the composition of matter for a new... Read More

Reported positive topline data from the completed Part A safety lead-in of the THIO-101 Phase 2 go-to-market trial in advanced Non-Small Cell Lung Cancer (NSCLC) and commenced recruitment in Part B randomized efficacy/dose selection Outlined preliminary safety data from Part A survival safety data from THIO-101 with first two enrolled patients alive after approximately 10 and 9 months post treatment initiation, respectively... Read More

NEW YORK / Apr 27, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA), a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer, today announced the closing of its previously announced public offering of 2,555,500 shares of its common stock at a public offering price of $2.25 per share, for gross proceeds of approximately $5.75 million, before deducting underwriting... Read More

CHICAGO / Apr 20, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) today announced preliminary survival data in the Part A safety lead-in of its ongoing phase 2 trial, THIO-101 evaluating THIO in patients with advanced Non-Small Cell Lung Cancer (NSCLC). The first 2 patients enrolled in Part A of the study continue to be alive, approximately 10 and 9 months respectively, from treatment initiation. Both... Read More

Study showed THIO with complete and durable responses in Hepatocellular Carcinoma (HCC), or the dominate histology in primary liver cancer (90%), in vivo models When combined with immunotherapy checkpoint inhibitor (CPI), duration of response was further potentiated Administration of THIO alone and in combination with CPI generated anti-cancer immune memory Upon rechallenge with two times more cancer cells and no additional... Read More

CHICAGO / Apr 12, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) today announced that it will present a poster that will feature the design of its ongoing Phase 2 clinical trial, THIO-101 evaluating THIO in patients with advanced Non-Small Cell Lung Cancer (NSCLC). The poster will be presented at the American Association for Cancer Research (AACR) Annual Meeting 2023, which is taking place in-person at... Read More

CHICAGO / Apr 11, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) today announced positive topline data from the completed Part A safety lead-in of the Company’s THIO-101 Phase 2 go-to-market trial in advanced Non-Small Cell Lung Cancer (NSCLC) and has commenced recruitment in Part B randomized efficacy/dose selection. Topline data from Part A demonstrated that MAIA’s telomere-targeting agent, THIO,... Read More

CHICAGO / Mar 13, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) announced today the Company has no exposure to Silicon Valley Bank (“SVB”). The Company is aware that the Federal Deposit Insurance Corp. has taken control of SVB due to liquidity concerns. The Company confirms it does not hold any deposits or investments at SVB, as well as at Silvergate Bank, or Signature Bank. MAIA’s cash is managed... Read More

CHICAGO / Mar 07, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA) announced today that the first two patients have been dosed in Europe in MAIA’s Phase 2 clinical trial, THIO-101 evaluating THIO in patients with advanced Non-Small Cell Lung Cancer (NSCLC). Following regulatory clearances in Hungary, Poland, and Bulgaria, five clinical sites have been activated in these three European countries. The... Read More

CHICAGO / Feb 13, 2023 / Business Wire / MAIA Biotechnology, Inc. (NYSE American: MAIA ) announced today it intends to initiate its second Phase 2 go-to-market trial evaluating THIO, the world’s first telomere-targeting agent, in patients with four cancer indications. The FDA has awarded MAIA’s lead anti-cancer agent THIO two Orphan Drug Designations, based on the preclinical efficacy data, for liver (hepatocellular... Read More

Progressing next generation of telomere-targeting candidates through proof of concept studies with promising anti-cancer activity Filed provisional new composition of matter patent during fourth quarter 2022 MAIA Biotechnology, Inc. (NYSE American: MAIA) announced today the advancement of its Telomere-Targeting Molecule Program (“Project T3”). MAIA is designing and evaluating multiple telomere-targeting compounds designed to... Read More

MAIA Biotechnology, Inc. (NYSE American: MAIA) (“MAIA,” “the Company”) announced today that the management team will participate in the four upcoming investor conferences as follows: Biotech Showcase: The Investor Conference for Innovators will be held in-person in San Francisco from January 9-11, and virtually from January 18-19. The MAIA team will host investor meetings and is scheduled to present on Monday, January 9 at... Read More

CHICAGO--( BUSINESS WIRE )-- MAIA Biotechnology, Inc. (NYSE American: MAIA) (“MAIA,” “the Company”) today announced that it completed a pre-Investigational New Drug (pre-IND) meeting with the U.S. Food and Drug Administration (FDA) for the planned U.S. expansion of the THIO-101 Phase 2 trial evaluating THIO, an investigational telomere-targeting agent, in patients with advanced non-small cell lung cancer (NSCLC). MAIA... Read More

Clinical trial evaluating MAIA Biotechnology’s lead therapeutic candidate in non-small cell lung cancer patients CHICAGO--( BUSINESS WIRE )-- MAIA Biotechnology, Inc. (NYSE American: MAIA) (“MAIA,” “the Company”), announced today that regulatory authorities in three European countries, Hungary, Poland, and Bulgaria, have approved the implementation of THIO-101, MAIA’s Phase 2 clinical trial evaluating its lead therapeutic... Read More