MAINZ, Germany, August 5, 2024 (GLOBE NEWSWIRE) -- BioNTech SE (Nasdaq: BNTX, “BioNTech” or “the Company”) today reported financial results for the three and six months ended June 30, 2024, and provided an update on its corporate progress.
“The year to date has been marked by significant data updates across our oncology portfolio. These readouts reinforce the potential of our platform technologies including our individualized and off-the-shelf mRNA vaccine platforms, iNeST and FixVac. We have also advanced our strategy by initiating clinical trials evaluating novel combinations of synergistic drug candidates. Notably, we dosed the first patient in a trial evaluating the combination of the TROP2 antibody-drug conjugate BNT325/DB-1305 and the PD-L1-VEGF-A bispecific BNT327/PM8002, aiming to harness the potent anti-tumor activity of antibody drug conjugates along with the sustained benefit of immunomodulators,” said Prof. Ugur Sahin, M.D., CEO and Co-Founder of BioNTech. “In addition, we have started commercializing variant-adapted COVID-19 vaccines for the upcoming season, while accelerating our clinical development efforts to realize the full potential of our technologies. We are making progress towards our goal of becoming a company with marketed medicines for cancer and infectious diseases.”
Financial Review for Second Quarter and First Half of 2024
in millions €, except per share data | Second Quarter 2024 | Second Quarter 2023 | First Half 2024 | First Half 2023 | ||||||||
Revenues | 128.7 | 167.7 | 316.3 | 1,444.7 | ||||||||
Net Profit / (Loss) | (807.8) | (190.4) | (1,122.9) | 311.8 | ||||||||
(Loss) / Diluted Earnings per Share | (3.36) | (0.79) | (4.67) | 1.28 |
Revenues reported were €128.7 million for the three months ended June 30, 2024, compared to €167.7 million for the comparative prior year period. For the six months ended June 30, 2024, revenues were €316.3 million, compared to €1,444.7 million for the comparative prior year period. The year-over-year change was mainly due to lower revenues from the sales of the Company’s COVID-19 vaccines worldwide resulting from the continued shift in demand from a pandemic to a seasonal endemic COVID-19 vaccine market.
Cost of sales were €59.8 million for the three months ended June 30, 2024, compared to €162.9 million for the comparative prior year period. For the six months ended June 30, 2024, cost of sales were €118.9 million, compared to €258.9 million for the comparative prior year period. The change was mainly due to COVID-19 vaccine production in line with demand.
Research and development (“R&D”) expenses were €584.6 million for the three months ended June 30, 2024, compared to €373.4 million for the comparative prior year period. For the six months ended June 30, 2024, R&D expenses were €1,092.1 million, compared to €707.4 million for the comparative prior year period. R&D expenses were mainly influenced by progressing clinical studies for the Company’s late-stage oncology pipeline candidates. Further contributions to the increase came from wages, benefits and social security expenses resulting from an increase in headcount.
Sales, general and administrative (“SG&A”) expenses2, in total, amounted to €183.8 million for the three months ended June 30, 2024, compared to €137.9 million for the comparative prior year period. For the six months ended June 30, 2024, SG&A expenses were €316.4 million, compared to €261.9 million for the comparative prior year period. SG&A expenses were primarily driven by increased expenses for IT environment and wages, benefits, and social security expenses resulting from an increase in headcount.
Other operating result amounted to €266.7 million negative operating result during the three months ended June 30, 2024, compared to €56.8 million negative operating result for the comparative prior year period. For the six months ended June 30, 2023, other operating result amounted to €262.3 million negative operating result compared with €125.4 million negative operating result for the prior year period. This change was primarily due to the recording of a provision related to a contractual dispute.
Income taxes were accrued with an amount of €2.0 million of tax expenses for the three months ended June 30, 2024, compared to €221.8 million of realized tax income for the comparative prior year period. For the six months ended June 30, 2024, income taxes were realized with an amount of €14.7 million of tax income for the six months ended June 30, 2024, compared to €16.3 million of realized tax income for the comparative prior year period. The effective income tax rate for the six months ended June 30, 2024, was approximately 1.3%.
Net loss was €807.8 million for the three months ended June 30, 2024, compared to €190.4 million loss for the comparative prior year period. For the six months ended June 30, 2024, loss was €1,122.9 million for the six months ended June 30, 2024, compared to a profit of €311.8 million for the comparative prior year period.
Cash and cash equivalents plus security investments as of June 30, 2024, reached €18,485.1 million, comprising €10,376.7 million cash and cash equivalents, €6,916.7 million current security investments and €1,191.7 million non-current security investments. This position increased during the second quarter of 2024 largely attributable to a cash payment received from BioNTech’s collaboration partner Pfizer Inc. (“Pfizer”).
Loss per share was €3.36 for the three months ended June 30, 2024, compared to €0.79 for the comparative prior year period. For the six months ended June 30, 2024, loss per share was €4.67, compared to diluted earnings per share of €1.28 for the comparative prior year period.
Shares outstanding as of June 30, 2024 were 237,766,235, excluding 10,785,965 shares held in treasury.
“Our second quarter revenues correspond to the current demand of a seasonal endemic COVID-19 vaccine market,” said Jens Holstein, CFO of BioNTech. “Supported by our strong financial position, we will continue to focus on our long-term growth strategy throughout the remainder of the year. This includes our clinical pipeline for individualized therapies, the build-out of our manufacturing capacities and capabilities to support additional late-stage trials as well as our commercialization activities. These investments build the foundation for the next stage of growth and the transformation of BioNTech into a multi-product company.”
2024 Financial Year Guidance3 Reiterated
The Company reiterates its prior outlook for the financial year:
Total revenues for the 2024 financial year | €2.5 billion - €3.1 billion |
BioNTech expects revenues for the full 2024 financial year to be in the range of €2.5 to €3.1 billion. The range reflects certain assumptions and expectations, including, but not limited to: the timing and granting of regulatory approvals and recommendations; COVID-19 vaccine uptake and price levels; inventory write-downs by BioNTech’s collaboration partner Pfizer that would negatively influence BioNTech’s revenues; seasonal variations in SARS-CoV-2 circulation and vaccination uptake, which are expected to lead to demand peaks in the autumn and winter compared to other seasons; and revenues from a pandemic preparedness contract with the German government as well as revenues from the BioNTech Group service businesses, namely InstaDeep Ltd., JPT Peptide Technologies GmbH, and in Idar-Oberstein at BioNTech Innovative Manufacturing Services GmbH. Generally, the Company continues to remain largely dependent on revenues generated in its collaboration partner’s territories in 2024.
Planned 2024 Financial Year Expenses and Capex:
R&D expenses4 | €2.4 billion - €2.6 billion | |||
SG&A expenses | €700 million - €800 million | |||
Capital expenditures for operating activities | €400 million - €500 million |
The full interim unaudited condensed consolidated financial statements can be found in BioNTech’s Report on Form 6-K for the period ended June 30, 2024, filed today with the United States Securities and Exchange Commission (“SEC”) and available at https://www.sec.gov/.
Endnotes
1 Calculated applying the average foreign exchange rate for the six months ended June 30, 2024, as published by the German Central Bank (Deutsche Bundesbank).
2 “SG&A expenses’’ includes sales and marketing expenses as well as general and administrative expenses.
3 Guidance excludes external risks that are not yet known and/or quantifiable. It does not include potential payments resulting from the outcomes of ongoing and/or future legal disputes or related activity, such as judgements or settlements, which may have a material effect on the Company’s results of operations and/or cash flows. BioNTech continues to expect to report a loss for the 2024 financial year and expects to recognize the vast majority of its full year revenues mostly in the fourth quarter.
4 Numbers include effects identified from additional collaborations or potential M&A transactions to the extent disclosed and are subject to update due to future developments.
Operational Review of the Second Quarter 2024, Key Post Period-End Events and Outlook
Variant-adapted Monovalent COVID-19 Vaccines (COMIRNATY®)
COVID-19 – Influenza Combination Vaccine Program
BNT162b2 + BNT161 is an mRNA-based combination vaccine program against COVID-19 and influenza being developed in collaboration with Pfizer.
Select Oncology Pipeline Highlights
Cancer Vaccine Programs
BNT111 is based on BioNTech’s FixVac platform, and is a wholly owned, systemically administered, off-the-shelf uridine mRNA-lipoplex based cancer vaccine candidate encoding shared melanoma associated antigens.
BNT113 is a cancer vaccine candidate based on FixVac’s platform encoding for shared antigens associated with Human Papilloma Virus (“HPV16+”) head and neck cancer.
Abstract Title: Exploratory efficacy and translational results from the safety run in of AHEAD-MERIT, a phase II trial of first line pembrolizumab plus the fixed-antigen cancer vaccine BNT113 in advanced HPV16+ HNSCC
Poster Date: September 14, 2024
Presentation Number: 877P
Author: C. N. F. Saba
Abstract Title: HARE-40: A phase I/II trial of therapeutic HPV vaccine (BNT113) in patients with HPV16 driven carcinoma
Mini-oral Date & Time: September 16, 2024, 11:15 - 11:20 a.m. CEST
Presentation Number: 999MMO
Author: C. Ottensmeier
Autogene cevumeran (BNT122) is a uridine mRNA-lipoplex based cancer vaccine candidate for individualized neoantigen-specific immunotherapy (“iNeST”) being developed in collaboration with Genentech, Inc. (“Genentech”), a member of the Roche Group (“Roche”).
Next-Generation Immune Checkpoint Immunomodulator Programs
BNT327/PM8002 is a bispecific antibody candidate combining PD-L1 checkpoint inhibition with VEGF-A neutralization and is being developed in collaboration with Biotheus Inc. (“Biotheus”).
Abstract Title: A Phase II Safety and Efficacy Study of PM8002/BNT-327 in Combination with Chemotherapy in Patients with EGFR-mutated NSCLC
Mini-oral Presentation Date & Time: September 14, 2024, 10:25 - 10:30 a.m. CEST
Presentation Number: 1255MO
Author: Y-L. Wu
Abstract Title: A Phase Ib/II Study to Assess the Safety and Efficacy of PM8002/BNT327 in Combination with Nab-Paclitaxel for First Line Treatment of Locally Advanced or Metastatic Triple-Negative Breast Cancer
Mini-oral Presentation Date & Time: September 16, 2024, 08:35 - 08:40 a.m. CEST
Presentation Number: 348MO
Author: J. Wu
Abstract Title: A Phase Ib/IIa Trial to Evaluate the Safety and Efficacy of PM8002/ BNT327, a Bispecific Antibody Targeting PD-L1 and VEGF-A, as a Monotherapy in Patients with advanced renal cell carcinoma
Poster Date: September 15, 2024
Presentation Number: 1692P
Author: X. Sheng
BNT311/GEN1046 (acasunlimab) is a potential first-in-class bispecific antibody candidate combining PD-L1 checkpoint inhibition with 4-1BB costimulatory activation that is being developed for the treatment of solid tumors.
Abstract Title: Dosing Regimen for Acasunlimab (DuoBody-PD-L1x4-1BB) In Combination with Pembrolizumab
Poster Presentation Date & Time: September 9, 2024, 18:30-20:00 PDT
Presentation Number: 845
Author: G. Bajaj
Abstract Title: Acasunlimab Alone or in Combination with Pembrolizumab for Previously Treated Metastatic Non-Small Cell Lung Cancer
Mini-oral Presentation Date & Time: September 10, 2024, 15:07 - 15:12 PDT
Presentation Number: 1309
Author: L. Paz-Ares
ADC Programs
BNT323/DB-1303 is an ADC candidate targeting Human Epidermal Growth Factor 2 (“HER2”) that is being developed in collaboration with Duality Biologics (Suzhou) Co. Ltd. (“DualityBio”).
BNT324/DB-1311 is an ADC candidate targeting B7H3 that is being developed in collaboration with DualityBio.
BNT326/YL202 is an ADC candidate targeting HER3 that is being developed in collaboration with MediLink Therapeutics (Suzhou) Co., Ltd. (“MediLink”).
Cell Therapy Programs
BNT211 consists of two investigational medicinal products: a CAR-T cell product candidate targeting Claudin-6 (“CLDN6”)-positive solid tumors in combination with a CAR-T cell-amplifying RNA vaccine (“CARVac”) encoding CLDN6.
Abstract Title: Updated results from BNT211-01 (NCT04503278), an ongoing, first-in-human, Phase 1 study evaluating safety and efficacy of CLDN6 CAR T cells and a CLDN6-encoding mRNA vaccine in patients with relapsed/refractory CLDN6+ solid tumors
Mini-oral Presentation Date & Time: September 15, 2024, 15:45 - 15:55 CEST
Presentation Number: 611O
Author: J. B. Haanen
Corporate Update for the Second Quarter 2024 and Key Post Period-End Events
Upcoming Investor and Analyst Events
Conference Call and Webcast Information
BioNTech invites investors and the general public to join a conference call and webcast with investment analysts today, August 5, 2024, at 8:00 a.m. EDT (2:00 p.m. CEST) to report its financial results and provide a corporate update for the second quarter of 2024.
To access the live conference call via telephone, please register via this link. Once registered, dial-in numbers and a PIN number will be provided.
The slide presentation and audio of the webcast will be available via this link.
Participants may also access the slides and the webcast of the conference call via the “Events & Presentations” page of the Investors' section of the Company’s website at www.BioNTech.com. A replay of the webcast will be available shortly after the conclusion of the call and archived on the Company’s website for 30 days following the call.
About BioNTech
Biopharmaceutical New Technologies (BioNTech) is a global next generation immunotherapy company pioneering novel therapies for cancer and other serious diseases. BioNTech exploits a wide array of computational discovery and therapeutic drug platforms for the rapid development of novel biopharmaceuticals. Its broad portfolio of oncology product candidates includes individualized and off-the-shelf mRNA-based therapies, innovative chimeric antigen receptor (CAR) T cells, several protein-based therapeutics, including bispecific immune checkpoint modulators, targeted cancer antibodies and antibody-drug conjugate (ADC) therapeutics, as well as small molecules. Based on its deep expertise in mRNA vaccine development and in-house manufacturing capabilities, BioNTech and its collaborators are developing multiple mRNA vaccine candidates for a range of infectious diseases alongside its diverse oncology pipeline. BioNTech has established a broad set of relationships with multiple global and specialized pharmaceutical collaborators, including Biotheus, DualityBio, Fosun Pharma, Genentech, a member of the Roche Group, Genevant, Genmab, MediLink, OncoC4, Pfizer and Regeneron.
For more information, please visit www.BioNTech.com.
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, but not limited to, statements concerning: BioNTech’s expected revenues related to sales of BioNTech’s COVID-19 vaccine, referred to as COMIRNATY where approved for use under full or conditional marketing authorization, in territories controlled by BioNTech’s collaboration partners, particularly for those figures that are derived from preliminary estimates provided by BioNTech’s partners; the rate and degree of market acceptance of BioNTech’s COVID-19 vaccine and, if approved, BioNTech’s investigational medicines; expectations regarding anticipated changes in COVID-19 vaccine demand, including changes to the ordering environment and expected regulatory recommendations to adapt vaccines to address new variants or sublineages; the initiation, timing, progress, results, and cost of BioNTech’s research and development programs, including BioNTech’s current and future preclinical studies and clinical trials, including statements regarding the timing of initiation, enrollment, and completion of studies or trials and related preparatory work and the availability of results, and the timing and outcome of applications for regulatory approvals and marketing authorizations; BioNTech’s expectations regarding potential future commercialization in oncology, including goals regarding timing and indications; the targeted timing and number of additional potentially registrational trials, and the registrational potential of any trial BioNTech may initiate; discussions with regulatory agencies; BioNTech’s expectations with respect to intellectual property; the impact of BioNTech’s collaboration and licensing agreements; the development, nature and feasibility of sustainable vaccine production and supply solutions; BioNTech’s estimates of revenues, research and development expenses, selling, general and administrative expenses and capital expenditures for operating activities; and BioNTech’s expectations of net profit / (loss). In some cases, forward-looking statements can be identified by terminology such as “will,” “may,” “should,” “expects,” “intends,” “plans,” “aims,” “anticipates,” “believes,” “estimates,” “predicts,” “potential,” “continue,” or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words.
The forward-looking statements in this press release are based on BioNTech’s current expectations and beliefs of future events, and are neither promises nor guarantees. You should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond BioNTech’s control and which could cause actual results to differ materially and adversely from those expressed or implied by these forward-looking statements. These risks and uncertainties include, but are not limited to: the uncertainties inherent in research and development, including the ability to meet anticipated clinical endpoints, commencement and/or completion dates for clinical trials, regulatory submission dates, regulatory approval dates and/or launch dates, as well as risks associated with preclinical and clinical data, including the data discussed in this release, and including the possibility of unfavorable new preclinical, clinical or safety data and further analyses of existing preclinical, clinical or safety data; the nature of the clinical data, which is subject to ongoing peer review, regulatory review and market interpretation; BioNTech’s pricing and coverage negotiations regarding its COVID-19 vaccine with governmental authorities, private health insurers and other third-party payors; the future commercial demand and medical need for initial or booster doses of a COVID-19 vaccine; competition from other COVID-19 vaccines or related to BioNTech’s other product candidates, including those with different mechanisms of action and different manufacturing and distribution constraints, on the basis of, among other things, efficacy, cost, convenience of storage and distribution, breadth of approved use, side-effect profile and durability of immune response; the timing of and BioNTech’s ability to obtain and maintain regulatory approval for its product candidates; the ability of BioNTech’s COVID-19 vaccines to prevent COVID-19 caused by emerging virus variants; BioNTech’s and its counterparties’ ability to manage and source necessary energy resources; BioNTech’s ability to identify research opportunities and discover and develop investigational medicines; the ability and willingness of BioNTech’s third-party collaborators to continue research and development activities relating to BioNTech's development candidates and investigational medicines; the impact of COVID-19 on BioNTech’s development programs, supply chain, collaborators and financial performance; unforeseen safety issues and potential claims that are alleged to arise from the use of products and product candidates developed or manufactured by BioNTech; BioNTech’s and its collaborators’ ability to commercialize and market BioNTech’s COVID-19 vaccine and, if approved, its product candidates; BioNTech’s ability to manage its development and expansion; regulatory developments in the United States and other countries; BioNTech’s ability to effectively scale its production capabilities and manufacture its products and product candidates; risks relating to the global financial system and markets; and other factors not known to BioNTech at this time.
You should review the risks and uncertainties described under the heading “Risk Factors” in BioNTech’s Report on Form 6-K for the period ended June 30, 2024 and in subsequent filings made by BioNTech with the SEC, which are available on the SEC’s website at www.sec.gov. These forward-looking statements speak only as of the date hereof. Except as required by law, BioNTech disclaims any intention or responsibility for updating or revising any forward-looking statements contained in this press release in the event of new information, future developments or otherwise.
Contacts
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Interim Consolidated Statements of Profit or Loss
Three months ended June 30, | Six months ended June 30, | |||||||||||
2024 | 2023 | 2024 | 2023 | |||||||||
(in millions €, except per share data) | (unaudited) | (unaudited) | (unaudited) | (unaudited) | ||||||||
Revenues | 128.7 | 167.7 | 316.3 | 1,444.7 | ||||||||
Cost of sales | (59.8) | (162.9) | (118.9) | (258.9) | ||||||||
Research and development expenses | (584.6) | (373.4) | (1,092.1) | (707.4) | ||||||||
Sales and marketing expenses | (12.9) | (18.1) | (28.5) | (30.3) | ||||||||
General and administrative expenses (1) | (170.9) | (119.8) | (287.9) | (231.6) | ||||||||
Other operating expenses (1) | (290.8) | (77.1) | (314.7) | (202.8) | ||||||||
Other operating income | 24.1 | 20.3 | 52.4 | 77.4 | ||||||||
Operating income / (loss) | (966.2) | (563.3) | (1,473.4) | 91.1 | ||||||||
Finance income | 167.7 | 152.4 | 345.3 | 208.9 | ||||||||
Finance expenses | (7.3) | (1.3) | (9.5) | (4.5) | ||||||||
Profit / (Loss) before tax | (805.8) | (412.2) | (1,137.6) | 295.5 | ||||||||
Income taxes | (2.0) | 221.8 | 14.7 | 16.3 | ||||||||
Profit / (Loss) for the period | (807.8) | (190.4) | (1,122.9) | 311.8 | ||||||||
Earnings / (Loss) per share | ||||||||||||
Basic earnings / (loss) for the period per share | (3.36) | (0.79) | (4.67) | 1.29 | ||||||||
Diluted earnings / (loss) for the period per share | (3.36) | (0.79) | (4.67) | 1.28 |
(1) Adjustments to prior-year figures due to change in functional allocation of general and administrative expenses and other operating expenses.
Interim Consolidated Statements of Financial Position
June 30, | December 31, | |||||
(in millions €) | 2024 | 2023 | ||||
Assets | (unaudited) | |||||
Non-current assets | ||||||
Goodwill | 372.4 | 362.5 | ||||
Other intangible assets | 862.3 | 804.1 | ||||
Property, plant and equipment | 868.6 | 757.2 | ||||
Right-of-use assets | 256.4 | 214.4 | ||||
Other financial assets | 1,386.1 | 1,176.1 | ||||
Other non-financial assets | 108.2 | 83.4 | ||||
Deferred tax assets | 102.3 | 81.3 | ||||
Total non-current assets | 3,956.3 | 3,479.0 | ||||
Current assets | ||||||
Inventories | 340.1 | 357.7 | ||||
Trade and other receivables | 75.8 | 2,155.7 | ||||
Contract assets | 3.9 | 4.9 | ||||
Other financial assets | 6,919.0 | 4,885.3 | ||||
Other non-financial assets | 359.3 | 280.9 | ||||
Income tax assets | 206.8 | 179.1 | ||||
Cash and cash equivalents | 10,376.7 | 11,663.7 | ||||
Total current assets | 18,281.6 | 19,527.3 | ||||
Total assets | 22,237.9 | 23,006.3 | ||||
Equity and liabilities | ||||||
Equity | ||||||
Share capital | 248.6 | 248.6 | ||||
Capital reserve | 1,232.3 | 1,229.4 | ||||
Treasury shares | (10.8) | (10.8) | ||||
Retained earnings | 18,640.4 | 19,763.3 | ||||
Other reserves | (1,038.2) | (984.6) | ||||
Total equity | 19,072.3 | 20,245.9 | ||||
Non-current liabilities | ||||||
Lease liabilities, loans and borrowings | 219.3 | 191.0 | ||||
Other financial liabilities | 42.1 | 38.8 | ||||
Provisions | 9.0 | 8.8 | ||||
Contract liabilities | 353.6 | 398.5 | ||||
Other non-financial liabilities | 77.9 | 13.1 | ||||
Deferred tax liabilities | 37.8 | 39.7 | ||||
Total non-current liabilities | 739.7 | 689.9 | ||||
Current liabilities | ||||||
Lease liabilities, loans and borrowings | 35.3 | 28.1 | ||||
Trade payables and other payables | 881.5 | 354.0 | ||||
Other financial liabilities | 146.0 | 415.2 | ||||
Income tax liabilities | 365.2 | 525.5 | ||||
Provisions | 363.9 | 269.3 | ||||
Contract liabilities | 474.3 | 353.3 | ||||
Other non-financial liabilities | 159.7 | 125.1 | ||||
Total current liabilities | 2,425.9 | 2,070.5 | ||||
Total liabilities | 3,165.6 | 2,760.4 | ||||
Total equity and liabilities | 22,237.9 | 23,006.3 |
Interim Consolidated Statements of Cash Flows
Three months ended June 30, | Six months ended June 30, | |||||||||||
2024 | 2023 | 2024 | 2023 | |||||||||
(in millions €) | (unaudited) | (unaudited) | (unaudited) | (unaudited) | ||||||||
Operating activities | ||||||||||||
Profit / (Loss) for the period | (807.8) | (190.4) | (1,122.9) | 311.8 | ||||||||
Income taxes | 2.0 | (221.8) | (14.7) | (16.3) | ||||||||
Profit / (Loss) before tax | (805.8) | (412.2) | (1,137.6) | 295.5 | ||||||||
Adjustments to reconcile profit before tax to net cash flows: | ||||||||||||
Depreciation and amortization of property, plant, equipment, intangible assets and right-of-use assets | 49.9 | 31.9 | 88.2 | 63.3 | ||||||||
Share-based payment expenses | 20.2 | 13.1 | 36.5 | 21.7 | ||||||||
Net foreign exchange differences | (13.2) | (397.0) | (41.9) | (343.9) | ||||||||
(Gain) / Loss on disposal of property, plant and equipment | (0.2) | 0.1 | (0.2) | 0.3 | ||||||||
Finance income excluding foreign exchange differences | (167.7) | (126.6) | (342.6) | (208.9) | ||||||||
Finance expense excluding foreign exchange differences | 4.8 | 1.3 | 9.5 | 2.5 | ||||||||
Government grants | (3.1) | — | (12.2) | (3.0) | ||||||||
Unrealized loss on derivative instruments at fair value through profit or loss(1) | 5.0 | 124.0 | 6.7 | 200.2 | ||||||||
Working capital adjustments: | ||||||||||||
Decrease in trade and other receivables, contract assets and other assets(1) | 1,599.6 | 4,137.0 | 2,097.8 | 5,030.8 | ||||||||
Decrease / (Increase) in inventories | 5.3 | (24.8) | 17.6 | (9.3) | ||||||||
(Decrease) / Increase in trade payables, other financial liabilities, other liabilities, contract liabilities, refund liabilities and provisions | 760.8 | 592.7 | 472.8 | (268.9) | ||||||||
Interest received and realized gains from cash and cash equivalents | 80.8 | 42.5 | 280.2 | 96.1 | ||||||||
Interest paid and realized losses from cash and cash equivalents | (1.6) | (1.3) | (5.3) | (2.5) | ||||||||
Income tax received / (paid), net(1) | 66.4 | 437.3 | (192.4) | (407.6) | ||||||||
Share-based payments | (6.8) | (31.3) | (9.2) | (757.0) | ||||||||
Government grants received | 32.8 | — | 42.0 | — | ||||||||
Net cash flows from operating activities | 1,627.2 | 4,386.7 | 1,309.9 | 3,709.3 | ||||||||
Investing activities | ||||||||||||
Purchase of property, plant and equipment | (88.6) | (67.2) | (147.1) | (112.4) | ||||||||
Proceeds from sale of property, plant and equipment | 0.2 | — | 0.2 | — | ||||||||
Purchase of intangible assets and right-of-use assets | (52.7) | (242.1) | (131.1) | (251.7) | ||||||||
Investment in other financial assets | (2,448.2) | (1,982.5) | (7,343.3) | (2,663.1) | ||||||||
Proceeds from maturity of other financial assets | 2,347.9 | — | 5,075.5 | — | ||||||||
Net cash flows used in investing activities | (241.4) | (2,291.8) | (2,545.8) | (3,027.2) | ||||||||
Financing activities | ||||||||||||
Repayment of loans and borrowings | (2.3) | — | (2.3) | — | ||||||||
Payments related to lease liabilities | (20.6) | (9.4) | (28.4) | (18.7) | ||||||||
Share repurchase program | — | (154.0) | — | (436.0) | ||||||||
Net cash flows used in financing activities | (22.9) | (163.4) | (30.7) | (454.7) | ||||||||
Net increase / (decrease) in cash and cash equivalents | 1,362.9 | 1,931.5 | (1,266.6) | 227.4 | ||||||||
Change in cash and cash equivalents resulting from exchange rate differences | (3.3) | 91.2 | 3.5 | 64.1 | ||||||||
Change in cash and cash equivalents resulting from other valuation effects | 40.5 | — | (23.9) | — | ||||||||
Cash and cash equivalents at the beginning of the period | 8,976.6 | 12,143.9 | 11,663.7 | 13,875.1 | ||||||||
Cash and cash equivalents as of June 30 | 10,376.7 | 14,166.6 | 10,376.7 | 14,166.6 |
(1) Adjustments to prior-year figures relate to reclassifications within the cash flows from operating activities.
Last Trade: | US$111.48 |
Daily Change: | -2.46 -2.16 |
Daily Volume: | 940,302 |
Market Cap: | US$26.510B |
September 05, 2024 July 30, 2024 |
Cue Biopharma is developing the first-ever class of therapeutics for the treatment of cancer that mimic the natural signals, or “Cues”, of the immune system. This novel class of injectable biologics selectively engages and modulates tumor-specific T cells directly within the patient’s body to transform...
CLICK TO LEARN MOREAstria Therapeutics is a biopharmaceutical company, and our mission is to bring life-changing therapies to patients and families affected by rare and niche allergic and immunological diseases. Our lead program, STAR-0215, is a monoclonal antibody inhibitor of plasma kallikrein in clinical development...
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